http://10.9.150.37:8080/dspace//handle/atmiyauni/474 2026-04-27T19:00:24Z 2026-04-27T19:00:24Z Baku, N. K. Ladva, K. D. Choleraa, A. Y. Travadic, J. J. http://10.9.150.37:8080/dspace//handle/atmiyauni/2282 2025-01-04T07:13:28Z 2024-01-01T00:00:00Z

Title: Eff ect of Laterally Substituted Methoxy Group on the Mesomorphic Behavior of Novel Ester Derivatives Authors: Baku, N. K.; Ladva, K. D.; Choleraa, A. Y.; Travadic, J. J. Abstract: To understand how molecular structure affects liquid crystal behavior with reference to the lateral methoxy group, a novel homologous series of liquid crystal derivatives was synthesized and analyzed. The homologous series consists of 12 derivatives (C1–C16), of which the first five homologs (C1–C5) are not liquid crystals, while the remaining homologs (C6–C16) are enantiotropically smectogenic liquid crystals without exhibiting the nematic phase. The average thermal stability of the smectic phase is 77.85°C, and the mesophase length ranges from 4 to 17°C. The molecular structures were verified by analytical and spectral data. The liquid crystal properties of the novel series were compared with those of structurally similar known homologous series. The transition temperatures were determined by an optical polarizing microscope equipped with a heating stage.

2024-01-01T00:00:00Z Akbari, Pankajkumar Madhavjibhai http://10.9.150.37:8080/dspace//handle/atmiyauni/2238 2025-01-01T13:09:54Z 2019-01-01T00:00:00Z

Title: Synthesis, Characterization and Biological Evaluation of Ethyl-4'-(cyclopropane carboxamido-N-yl)-5-ary-3-oxo-3,4,5,6-tetrahydro-biphenyl-4-carboxylate Authors: Akbari, Pankajkumar Madhavjibhai Abstract: A series of new substituted cyclohexenone derivatives have been synthesized by the reaction of various substituted chalcones with ethylacetoacetate. Some new N-(4-(3-aryl-acryloyl)phenyl)cyclopropane carboxamide were prepared by Claisen-Schmidt condensation method in presence of sodium hydroxide in ethanol solvent under stirring. The synthesized compounds were characterized by their spectral (IR, NMR, Mass) data and screened for their antimicrobial activities against Gram-positive and Gram-negative bacteria by using standard antimicrobial drugs.

2019-01-01T00:00:00Z Hadiyal, Sanjay http://10.9.150.37:8080/dspace//handle/atmiyauni/2207 2025-01-01T11:30:33Z 2022-01-01T00:00:00Z

Title: Microwave-Assisted Synthesis of Some Novel 1,2,3,4-Tetrahydropyrimidine Derivatives as Antidiabetic Agents Authors: Hadiyal, Sanjay Abstract: An efficient and rapid microwave irradiation protocol have been developed for the synthesis of a new series of N-(4-R-phenyl)-6-methyl-4-(4-{[5-(4-nitrophenyl)-1,3,4-oxadiazol-2-yl]methoxy}phenyl)-2-oxo-3-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxamides. The synthesized compounds were evaluated for their in vitro antidiabetic activity by the α-amylase inhibition assay, and some derivatives exhibited a significant antidiabetic activity.

2022-01-01T00:00:00Z Jani, Darshan Raja, Maulik http://10.9.150.37:8080/dspace//handle/atmiyauni/2159 2025-01-01T08:04:15Z 2023-01-01T00:00:00Z

Title: Sulpha Drugs based Heterochelates: Synthesis, Spectroscopic, Thermal and In-vitro Biological Studies Authors: Jani, Darshan; Raja, Maulik Abstract: In the current study, dapsone and different 4-Acyl pyrazolone derivatives were used to synthesise various Cu(II) and Ni(II) based heterochelates. Elemental analysis, 1H NMR, IR, and mass spectroscopy were utilized to check the structure of the tetra dentate DPL1 to DPL5 ligands, and FAB mass spectroscopy as well as temperature investigations (TGA/DTG and DSC) were utilized to approve the structure of the Cu(II) and Ni(II) heterochelates. All the synthesized compounds were examined for their in-vitro biological study against two Gram +ve (Bacillus cereus, Bacillus megaterium) and two Gram-ve (Escherichia coli, Enterobacter aerogene) microorganisms as well as their MIC against two Gramme +ve (Bacillus subtilis, Staphylococcus aureus) and two Gram-ve (Escherichia coli, Serratia marcescens) microorganisms. The outcomes demonstrated the tremendous promise and importance of novel bis-pyrazolone heterochelates based on dapsone for further study.

2023-01-01T00:00:00Z