http://10.9.150.37:8080/dspace//handle/atmiyauni/1209 Mon, 27 Apr 2026 18:51:04 GMT 2026-04-27T18:51:04Z http://10.9.150.37:8080/dspace//handle/atmiyauni/1224 Title: Studies on Antagonistic Effect of Endophytic Bacteria against Human Resistant Pathogenic Bacteria Authors: Bakraniya, Harmi D. Abstract: The study aimed to isolate and screen Endophytic bacteria from various medicinal plants for their potential antimicrobial activity against human pathogenic bacteria. This provides insight into the potential of endophytic bacteria as a source of novel antibiotics to overcome the growing problem of antimicrobial resistance. The plant samples were collected from Atmiya University's medicinal garden and processed them using surface sterilization procedures. The collected endophytic bacteria were then subjected to primary and secondary screenings to determine their antimicrobial activity. 10 bacterial colonies were isolated, and only one colony showed a zone of inhibition (ZOI) against one human pathogenic bacteria, Enterobacteriaceae (M3). Sun, 01 Jan 2023 00:00:00 GMT http://10.9.150.37:8080/dspace//handle/atmiyauni/1224 2023-01-01T00:00:00Z http://10.9.150.37:8080/dspace//handle/atmiyauni/1223 Title: Isolation, Screening and Morphological Identification of Fungal L-Methionase from Ripen Fruits and Vegetables Authors: Kava, Devarsh S.; Modi, Kinjal C. Abstract: L-Methionase is one of the few microbial enzymes with high therapeutic value since it has been reported as a effective anticancer agent against many types of tumor cell lines like breast, lung, colon, kidney and glioblastoma. L-Methionase is present in all organisms except in mammals. It mainly catalyzes the α, ϒ-elimination of L-Methionase to α-ketobutyrate, Methanethiol and ammonia. L-Methionase producing fungi was isolated from ripen fruits and vegetables. We obtain total 24 fungal isolates from ripen fruits and vegetables. Quantitative rapid plate assay test shows the ability of 7 of these isolates to grow with yellow zone surrounding their colonial growth, while 17 of these isolates could grow and utilize L-Methionine without any yellow zone around their colonial growth. Quantitative assay test shows the rate of L-Methionine production by all isolates tested. Nesslerization assay for detection of ammonia isolate no. MFL 24 (2.95 μmol/min/ml) and isolate MFL no. 9 (3.45 μmol/min/ml) show highest L-Methionase enzyme activity. The identification of fungi was carried out by macroscopic and microscopic examinations depend on the colony color, shape, hyphae, conidia, conidiophores and arrangement of spores. Sun, 01 Jan 2023 00:00:00 GMT http://10.9.150.37:8080/dspace//handle/atmiyauni/1223 2023-01-01T00:00:00Z http://10.9.150.37:8080/dspace//handle/atmiyauni/1222 Title: Virtual screening of potent ligand against diabetes type 2 Authors: Chavda, Krupali; Makdiya, Hetvi; Mungra, Sneha Sun, 01 Jan 2023 00:00:00 GMT http://10.9.150.37:8080/dspace//handle/atmiyauni/1222 2023-01-01T00:00:00Z http://10.9.150.37:8080/dspace//handle/atmiyauni/1221 Title: Isolation, screening and characterization of microorgansim with fibrinolytic activity from various fermented foods Authors: Trivedi, Malvika; Chauhan, Sweta; Makwana, Priyanka; Jarsaniya, Krushi Abstract: One of the major problems of causes of death worldwide is cardiovascular disease, according to the American heart association. An unwanted blood clot (thrombi) is caused by dysregulation in the blood clotting system caused by abnormalities in the blood that provoke thrombosis and lead to heart attack, strokes, blocking of blood vessels and coronary artery disease etc. An Increasing percentage of deaths due to thrombosis. Commonly treat thrombosis different thrombolysis agents are used. A huge potential has a thrombolytic agent and it plays a major role. The fibrinolytic enzyme is considered a potent thrombolytic agent to treat and prevent cardiovascular diseases (CVDs). The commercially available thrombolytic agents such as Urokinase plasminogen activator, Streptokinase plasminogen activator and tissue plasminogen activator are generally safe but are very expensive and are less effective. Thrombolytic agents are of two types, one is plasmin like proteins which directly degrade fibrin and another one is plasminogen activator which activates plasminogen into active plasmin to degrade fibrin. The molecular weights of the proteins that play roles in the fibrinolytic activity ranged from approximately 30 to 153 kDa. The health benefits of some fermented foods are a synthesis of nutrients, prevention of cancer and cardiovascular disease due to the presence of functional microorganisms, which possess probiotics properties and anticoagulant. The fermented foods as sources of microorganism used were Rice water, Dhokla, Idli water. The total positive number of isolates were 27, out of which only 7 had significant proteolytic activity for fibrinolysis. Sun, 01 Jan 2023 00:00:00 GMT http://10.9.150.37:8080/dspace//handle/atmiyauni/1221 2023-01-01T00:00:00Z