Formulation Development and Evaluation of Polyherbal Gel Containing Extract of Eclipta Alba (L.) (Asteraceae) For The Management of Alopecia

Abstract

It is well known that Eclipta alba (L.) plant thrives best in climates that can be classified as either tropical or subtropical. The Hassak plant, belonging to the Asteraceae family, holds considerable importance in the field of medicine. The application of this specific therapeutic approach is frequently noticed in the care of various skin, liver, and gastrointestinal disorders in nations such as India, Nepal, Bangladesh, and other comparable countries. The main aim of this paper was to gather and examine the current body of literature regarding the biological functions, phytoconstituents, and traditional uses of E. alba. The compilation of scientific literature involved the utilisation of various resources such as books, proceedings, and electronic bibliographic databases like Scopus, MEDLINE/PubMed, Google Scholar, and SciFinder. The investigation identified several active phytochemicals, including phenolic acid, flavonoids, triterpenoid saponins, steroid saponins, and substituted thiophenes. Different extracts and chemicals isolated from E. alba have shown a wide range of biological properties, such as the ability to fight bacteria and cancer, protect the liver and brain, and promote hair growth. The study provides strong evidence to justify the utilization of a botanical blend in the context of hair care therapy. Hence, the botanical specimen could be regarded as an organic reservoir and potentially harnessed to develop an alternative therapeutic approach for alopecia.