| Title: | Synthesis of Pyrrole Derivatives via Cycloaddition Reaction of Reissert Hydrofluoroborate Salts with α-Bromoacrylamides |
| Authors: | Rathod, Chirag H. Patel, Anilkumar S. |
| Issue Date: | 2021 |
| Publisher: | Analytical Chemistry Letters |
| Citation: | Rathod, C. H., & Patel, A. S. (2021). Synthesis of Pyrrole Derivatives via Cycloaddition Reaction of Reissert Hydrofluoroborate Salts with α-Bromoacrylamides. Analytical Chemistry Letters, 11(3), 289-302. |
| Abstract: | Abstract An investigation of α-bromoacrylamide as a dienophile for the cycloaddition reaction of Reissert hydrofluoroborate salt of quinoline/phenanthridine has been carried out. The optimized condition has been developed for the [4+2] cycloaddition reaction of Reissert hydrofluroborate salt and α-bromoacrylamide by using K2CO3 in DMF under moderate temperature to afford highly functionalized pyrrole derivatives (6a-f and 7a-f) in very good to excellent yield. The structures of newly synthesized compounds were established based on FT-IR, Mass, 1H and 13C NMR spectral techniques. Besides, the structure of compound 7a has been confirmed by 2D NMR experiments (COSY and HSQC). |
| URI: | http://10.9.150.37:8080/dspace//handle/atmiyauni/1534 |
| Appears in Collections: | 01. Journal Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Synthesis of Pyrrole Derivatives via Cycloaddition Reaction of Reissert Hydrofluoroborate Salts with α-Bromoacrylamides.pdf | 1.78 MB | Adobe PDF | View/Open |
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