| Title: | Synthesis of Substituted 4-(4-((3-Nitro-2-oxo-2H-chromene-4-yl)amino)phenyl)morpholine-3-one Coumarin Derivatives |
| Authors: | Sanghani, Yogesh J. Koradiya, Suresh B. Patel, Anilkumar S. |
| Keywords: | 4-Chloro-3-nitro-2H-chromene-2-one 4-(4-Amino phenyl)morpholine-3-one 4-Hydroxy coumarin |
| Issue Date: | 2019 |
| Publisher: | Asian Journal of Chemistry |
| Citation: | Sanghani, Y. J., Koradiya, S. B. and Patel, A. S. (2019). Synthesis of Substituted 4-(4-((3-Nitro-2-oxo-2H-chromene-4-yl)amino)phenyl)morpholine-3-one Coumarin Derivatives. Asian Journal of Chemistry, 31(7), 1461-1464. |
| Series/Report no.: | ;31(7), 1461-1464 |
| Abstract: | A series of novel 4-(4-amino phenyl) morpholine-3-one substituted coumarin derivatives have been prepared by chloramine coupling reaction and were identified. The novel synthetic route involves nucleophilic substitution reaction of 4-chloro-3-nitro-2H-chromene-2-one with 4-(4-amino phenyl)morpholine-3-one. Due to the presence of nitro group in coumarin derivatives make substitution reaction easy and convenient at low temperature. Using DMF as solvent and K2 CO3 as base various substituted 4-(4-((3-nitro-2-oxo-2H-chromen-4-yl)amino)phenyl)morpholine-3-one derivatives (YS-1 to YS-10) can be obtain in good yield and high purity. Structural characterization of all synthesized compound was done by NMR, Mass and IR spectra |
| URI: | http://10.9.150.37:8080/dspace//handle/atmiyauni/1596 |
| Appears in Collections: | 01. Journal Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Synthesis of Substituted 4-(4-((3-Nitro-2-oxo-2H-chromene-4-.pdf | 538.48 kB | Adobe PDF | View/Open |
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