| Title: | Etidronic acid catalyzed simple, facile and generalized synthetic protocol for preparation of 2-substituted-1H-benzo[d]imidazole-6-carboxylates |
| Authors: | Ambasana, P. A. Nariya, N. P. Naliyapara, P. B. Vaghasiya, Y. T. Patel, A. S. |
| Keywords: | Homogenous catalyst bisphosphonate microwave assisted organic synthesis zimidazoles, and fused heterocycles. |
| Issue Date: | 2018 |
| Publisher: | Chemistry & Biology Interface |
| Citation: | Ambasana, P. A., Kapuriya, N. P., Nariya, P. B., Naliyapara, Y. T., Vaghasiya, R. G., & Patel, A. S. (2018). Etidronic acid catalyzed simple, facile and generalized synthetic protocol for preparation of 2-substituted-1H-benzo [d] imidazole-6-carboxylates. Chemistry & Biology Interface, 8(5). |
| Abstract: | A facile and efficient cyclo-condensation reaction of substituted ortho-phenylenediamines with an aldehyde or carboxylic acid using etidronic acid to furnish hitherto unreported Methyl 4-methyl-2-sub-stituted-1H-benzo[d]imidazole-6-carboxylatederivatives was described. A new and efficient protocol was developed as a homogenous catalyst for the synthesis of benzimidazoles under conventional and micro- wave irradiated reaction atmosphere. This methodology has the advantage of excellent yields with short reaction time and highly robust & practical reaction arrangement. |
| URI: | http://10.9.150.37:8080/dspace//handle/atmiyauni/1622 |
| Appears in Collections: | 01. Journal Articles |
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