Please use this identifier to cite or link to this item: http://10.9.150.37:8080/dspace//handle/atmiyauni/693
Title: Synthesis of Some New 2-Amino/Methoxy-4-(3- Methoxy-4-((3-Methyl-4-(2,2,2-Trifluoroethoxy) Pyridin-2-Yl) Methoxy) Phenyl)-6- Arylnicotinonitrile Derivative and Its Biological Activity
Authors: Patel, Piyush A.
Kakadiya, Sandip P.
Bhadani, Vijay N.
Purohit, Heta D.
Bhatt, Parth V.
Purohit, Dipak M.
Keywords: 2-Amino-3-cyanopyridine, 2-Methoy-3-cyanopyridine, Antimicrobial activity.
Issue Date: 1-Nov-2017
Publisher: International Journal for Research in Applied Science & Engineering Technology
Citation: Patel, P. A., Bhadani, V. N., Purohit, H. D., Bhatt, P. V., & Purohit, D. M. (2015). Synthesis of Some new2-Amino/Methoxy-4-(3-methoxy-4-((3-methyl-4-(2, 2, 2-trifluoroethoxy) pyridin-2-yl) methoxy) phenyl)-6-arylnicotinonitrileDerivative and its biological activity. Chemistry & Biology Interface, 5(6).
Abstract: A series of novel 2-Amino-3-cyanopyridine derivatives 2a-l and 2-Methoy-3-cyanopyridine derivatives 3a-l have been synthesized as potential antibacterial agents. The 2-Amino-3-cyanopyridine derivatives 2a-l have been synthesized by reaction of various Chalcones 1a-l with malononitrile and ammonium acetate in Ethanol. The 2-Methoy-3-cyanopyridine 3a-l were prepared by the reaction of Chalcone with malononitrile and sodium methoxide in Methanol. The structures of the new compounds were established on the basis of 1H-NMR, Mass, IR and elemental analysis data. All the newly synthesized compounds were screened for their antibacterial activity against E. coli, S. thyphi (Gram-negative bacteria), S. aureus, M. luteus (Gram-positive bacteria) and antifungal activity against Candida albicans (Fungi).
URI: https://www.ijraset.com/archive-detail.php?AID=64
http://10.9.150.37:8080/dspace//handle/atmiyauni/693
ISSN: 2321-9653
Appears in Collections:01. Journal Articles

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