Synthesis and Characterization of Novel Trisubstituted N-(2-methoxy-4-nitrophenyl)-1-phenyl-5-aryl-1 H-pyrazol-3-Amine Derivatives

Abstract

A series of novel trisubstituted pyrazole N-(2-methoxy-4-nitrophenyl)-1- phenyl-5-aryl-1H-pyrazol-3-amine derivatives have been synthesized by the reaction of substituted various novel cinnamamides with phenyl hydrazine. Various cinnamamide were prepared by condensation of appropriate 2-methoxy-4-nitroacetanilide with substituted aldehydes in the presence of sodium hydroxide in ethanol solvent under reflux. We are demonstrating the convenient process for synthesis novel trisubstituted N-(2-methoxy-4-nitrophenyl)-1-phenyl-5-aryl-1H-pyrazol-3-amine derivatives in high yield.