| Title: | Synthesis of pyrrole derivatives via cycloaddition reaction of reissert hydrofluoroborate salts with α-bromoacrylamides |
| Authors: | Rathod, Chirag H. Patel, Anilkumar S. |
| Keywords: | Reissert hydrofluoroborate salt Pyrrole derivatives Cycloaddition reaction α-Bromoacrylamides |
| Issue Date: | 2021 |
| Publisher: | Analytical Chemistry Letters, Taylor & Francis |
| Citation: | Rathod, C. H., & Patel, A. S. (2021). Synthesis of Pyrrole Derivatives via Cycloaddition Reaction of Reissert Hydrofluoroborate Salts with α-Bromoacrylamides. Analytical Chemistry Letters, 11(3), 289-302. |
| Abstract: | An investigation of α-bromoacrylamide as a dienophile for the cycloaddition reaction of Reissert hydrofluoroborate salt of quinoline/phenanthridine has been carried out. The optimized condition has been developed for the [4+2] cycloaddition reaction of Reissert hydrofluroborate salt and a-bromoacrylamide by using K2 CO3 in DMF under moderate temperature to afford highly functionalized pyrrole derivatives (6a-f and 7a-f) in very good to excellent yield. The structures of newly synthesized compounds were established based on FT-IR, Mass, 1 H and 13C NMR spectral techniques. Besides, the structure of compound 7a has been confirmed by 2D NMR experiments (COSY and HSQC). |
| Description: | Authors are thankful to the School of Science, RK University & Faculty of Science, Atmiya University, Rajkot for providing a laboratory experiment facility. We also thank to the Central Instrumental facility (CIF), Shree M. & N. Virani Science College (Autonomous) for providing spectral analysis. |
| URI: | http://10.9.150.37:8080/dspace//handle/atmiyauni/861 |
| ISSN: | 2230-7532 |
| Appears in Collections: | 01. Journal Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 204) 72869_Anilkumar Sundarjibhai Patel.pdf | 1.78 MB | Adobe PDF | View/Open |
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