Synthesis, spectroscopic, thermal and In-Vitro biological studies of some transition metal based heterochelates

Abstract

4-acyl pyrazolone derivatives and their heterochelates are well known for their thermal fluorescence and biological activity. However, here we represent the biological and thermal studies of some 4-acyl bis pyrazolone Schiff bases as ligand and their transition metal heterochelates. Structural and spectroscopic properties have been studied on the basis of elemental analysis, FT-IR, 1H-NMR spectral studies. The ligand and their heterochelate were screened for their in vitro antibacterial activity against range of Gram+ve (Bacillus cerus, Bacillus Magaterium) and Gram-ve (E.coli, E.aerogens) organisms.